ICriterion[] parameters = { Expression.Or(Expression.Like("Profile", search, MatchMode.Anywhere), Expression.Like("Location.Description", search, MatchMode.Anywhere)) };

{"could not resolve property: Location.Description of: careers.core.domain.intdir.DirectoryEntry"}

<?xml version="1.0" encoding="utf-8" ?>
<hibernate-mapping xmlns="urn:nhibernate-mapping-2.0">
  <class name="careers.core.domain.intdir.DirectoryEntry,careers.core" lazy="false"  table="idInternationalDirectory">

    <id name="Id" column="ID" type="Int32" unsaved-value="0">
      <generator class="native"/>
    </id>


    <property column="ClientID" type="Int32" name="Clientid" not-null="true" />
    <many-to-one name="Location"  class="careers.core.domain.intdir.Location,careers.core" column="HESAID"/>

    <property column="Profile" type="String" name="Profile" not-null="true" length="2000" />
    <property column="url" type="String" name="Url" not-null="true" length="50" />

    <set name="Tows"  table="idTowLookup">
      <key column="entryID" />
      <many-to-many column="TOWID" class="careers.core.domain.intdir.Tow,careers.core" />
    </set>

  </class>

  <query name="DirectoryEntry.Search">from DirectoryEntry de where (de.Client.ClientName = ? or de.Profile = ?) </query>

 
</hibernate-mapping>

<?xml version="1.0" encoding="utf-8" ?>
<hibernate-mapping xmlns="urn:nhibernate-mapping-2.0">
  <class name="careers.core.domain.intdir.Location,careers.core" lazy="false" table="Location">

    <id name="HesaId" column="HESA_id" type="Int32" unsaved-value="0">
      <generator class="assigned"/>
    </id>

    <property column="description" type="String" name="Description" length="255" />

  </class>

  <query name="Location.GetAll">from Location order by Description</query>
  <query name="Location.GetAllUsed">select distinct de.Location from DirectoryEntry de</query>

</hibernate-mapping>

<query name="DirectoryEntry.Search">from DirectoryEntry de where de.Client.ClientName like ? or de.Profile like ?</query>

#if NET_2_0
      public override IList<T> List<T>()
      {
         VerifyParameters();
         IDictionary namedParams = NamedParams;
         Before();
         try
         {
            return Session.Find<T>(BindParameterLists(namedParams), GetQueryParameters(namedParams));
         }
         finally
         {
            After();
         }
      }
#endif