I am not sure I understand your question fully because it's not entirely clear.
I am guessing that you want to change the database without using your application or bypassing the application.
Each or most modern database has a view application that connects to the database and allows you to browse each table and view each column. These viewers often allow you to modify the columns already existing. If you know what you are doing, you can even add new objects (new rows) with data, or delete objects,....etc.
So depending on your database, find the viewer application. For example for Microsoft SQL Sever - Revision 2 (higly recommended), the application is named Microsoft SQL Server Management Studio. It is free and can be downloaded and installed.
I hope that answers your question or gives you avenues of solutions.
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